basic/src/DetectorConstruction.cc

0001 //
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0025 //
0026 // The `molcounters` example(s) are provided as part of Geant4-DNA
0027 // and any report or published result obtained using it shall cite
0028 // the respective Geant4-DNA collaboration publications.
0029 //
0030 // Reports or results obtained using the spatially-aware `MoleculeCounter`
0031 // provided in this example, shall further cite:
0032 //
0033 // Velten & Tomé, Radiation Physics and Chemistry, 2023 (10.1016/j.radphyschem.2023.111194)
0034 //
0035 //
0036 // Author: Christian Velten (2025)
0037 //
0038
0039 #include "DetectorConstruction.hh"
0040
0041 #include "G4Box.hh"
0042 #include "G4Ellipsoid.hh"
0043 #include "G4LogicalVolume.hh"
0044 #include "G4NistManager.hh"
0045 #include "G4Orb.hh"
0046 #include "G4PVPlacement.hh"
0047 #include "G4PhysicalConstants.hh"
0048 #include "G4PhysicalVolumeStore.hh"
0049 #include "G4SystemOfUnits.hh"
0050 #include "G4VPhysicalVolume.hh"
0051 #include "Randomize.hh"
0052 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
0053 G4VPhysicalVolume* DetectorConstruction::Construct()
0054 {
0055   // Water is defined from NIST material database
0056   auto man = G4NistManager::Instance();
0057   auto water = man->FindOrBuildMaterial("G4_WATER");
0058
0059   //
0060   // World
0061   //
0062   const G4double worldXYZ = 1 * m;
0063
0064   auto solidWorld = new G4Box("World", 0.5 * worldXYZ, 0.5 * worldXYZ, 0.5 * worldXYZ);
0065   auto lvWorld = new G4LogicalVolume(solidWorld, water, "World");
0066   auto pvWorld =
0067     new G4PVPlacement(nullptr, G4ThreeVector(), lvWorld, "World", nullptr, false, 0, true);
0068
0069   //
0070   // Cell
0071   ConstructCell(pvWorld);
0072
0073   // return the world
0074   return pvWorld;
0075 }
0076 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
0077 void DetectorConstruction::ConstructCell(G4VPhysicalVolume* pvWorld)
0078 {
0079   const G4double cellRadius = 7 * um;
0080   const G4double nucleusRadius = 4 * um;
0081
0082   const G4int nMitochondria = 100;
0083   const G4double mitoA = 0.55 * micrometer;
0084   const G4double mitoB = 0.25 * micrometer;
0085   const G4double mitoC = 0.90 * micrometer;
0086
0087   auto solidCell = new G4Orb("Cell", cellRadius);
0088   auto lvCell = new G4LogicalVolume(
0089     solidCell, G4NistManager::Instance()->FindOrBuildMaterial("G4_WATER"), "Cell");
0090   auto pvCell =
0091     new G4PVPlacement(nullptr, G4ThreeVector(), "Cell", lvCell, pvWorld, false, 0, true);
0092
0093   auto solidNucleus = new G4Orb("Nucleus", nucleusRadius);
0094   auto lvNucleus = new G4LogicalVolume(
0095     solidNucleus, G4NistManager::Instance()->FindOrBuildMaterial("G4_WATER"), "Nucleus");
0096
0097   new G4PVPlacement(nullptr, G4ThreeVector(), "Nucleus", lvNucleus, pvCell, false, 0, true);
0098
0099   auto solidMito = new G4Ellipsoid("Mitochondria", mitoA, mitoB, mitoC);
0100   auto lvMito = new G4LogicalVolume(
0101     solidMito, G4NistManager::Instance()->FindOrBuildMaterial("G4_WATER"), "Mitochondria");
0102
0103   for (auto i = 0; i < nMitochondria; ++i) {
0104     G4bool overlap = true;
0105     do {
0106       auto u = twopi * G4UniformRand();
0107       auto v = std::acos(2 * G4UniformRand() - 1);
0108       auto dr = G4UniformRand() * cellRadius;
0109       auto x = dr * std::cos(u) * std::sin(v);
0110       auto y = dr * std::sin(u) * std::sin(v);
0111       auto z = dr * std::cos(v);
0112       auto pos = G4ThreeVector(x, y, z);
0113
0114       auto phi = G4UniformRand() * 2 * pi;
0115       auto psi = G4UniformRand() * 2 * pi;
0116       auto rot = new G4RotationMatrix();
0117       rot->rotateX(psi);
0118       rot->rotateY(phi);
0119
0120       auto pvMito = new G4PVPlacement(rot, pos, "Mitochondria", lvMito, pvCell, false, i, false);
0121
0122       overlap = pvMito->CheckOverlaps(1000, 0, false);
0123       if (overlap) {
0124         G4PhysicalVolumeStore::DeRegister(pvMito);
0125       }
0126     } while (overlap);
0127   }
0128 }
0129 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......