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0001 //
0002 // ********************************************************************
0003 // * License and Disclaimer                                           *
0004 // *                                                                  *
0005 // * The  Geant4 software  is  copyright of the Copyright Holders  of *
0006 // * the Geant4 Collaboration.  It is provided  under  the terms  and *
0007 // * conditions of the Geant4 Software License,  included in the file *
0008 // * LICENSE and available at  http://cern.ch/geant4/license .  These *
0009 // * include a list of copyright holders.                             *
0010 // *                                                                  *
0011 // * Neither the authors of this software system, nor their employing *
0012 // * institutes,nor the agencies providing financial support for this *
0013 // * work  make  any representation or  warranty, express or implied, *
0014 // * regarding  this  software system or assume any liability for its *
0015 // * use.  Please see the license in the file  LICENSE  and URL above *
0016 // * for the full disclaimer and the limitation of liability.         *
0017 // *                                                                  *
0018 // * This  code  implementation is the result of  the  scientific and *
0019 // * technical work of the GEANT4 collaboration.                      *
0020 // * By using,  copying,  modifying or  distributing the software (or *
0021 // * any work based  on the software)  you  agree  to acknowledge its *
0022 // * use  in  resulting  scientific  publications,  and indicate your *
0023 // * acceptance of all terms of the Geant4 Software license.          *
0024 // ********************************************************************
0025 //
0026 // This example is provided by the Geant4-DNA collaboration
0027 // dnadamage3 example is derived from the chem6 example
0028 // chem6 example authors: W. G. Shin and S. Incerti (CENBG, France)
0029 //
0030 // Any report or published results obtained using the Geant4-DNA software
0031 // shall cite the following Geant4-DNA collaboration publication:
0032 // Med. Phys. 37 (2010) 4692-4708
0033 // J. Comput. Phys. 274 (2014) 841-882
0034 // The Geant4-DNA web site is available at http://geant4-dna.org
0035 //
0036 // Authors: J. Naoki D. Kondo (UCSF, US)
0037 //          J. Ramos-Mendez and B. Faddegon (UCSF, US)
0038 //
0039 /// \file ScoreStrandBreaks.hh
0040 /// \brief Definition of the ScoreStrandBreaks class
0041 
0042 #ifndef DNADAMAGE2_ScoreSB_h
0043 #define DNADAMAGE2_ScoreSB_h 1
0044 
0045 #include "DetectorConstruction.hh"
0046 #include "MoleculeInserter.hh"
0047 
0048 #include "G4DNAIRT.hh"
0049 #include "G4THitsMap.hh"
0050 #include "G4UIcmdWithADoubleAndUnit.hh"
0051 #include "G4UIcmdWithAString.hh"
0052 #include "G4UIcmdWithAnInteger.hh"
0053 #include "G4UImessenger.hh"
0054 #include "G4VPrimitiveScorer.hh"
0055 
0056 class G4VAnalysisManager;
0057 class G4MolecularConfiguration;
0058 
0059 typedef std::map<G4int, std::map<G4int, std::map<G4int, std::map<G4int, G4double>>>>
0060   EnergyDepositMap;
0061 typedef std::map<G4int, std::vector<std::vector<G4int>>> DamageMap;
0062 
0063 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
0064 
0065 class ScoreStrandBreaks : public G4VPrimitiveScorer, public G4UImessenger
0066 {
0067   public:
0068     ScoreStrandBreaks(G4String name, DetectorConstruction*, G4double*);
0069     ~ScoreStrandBreaks() override;
0070 
0071     void WriteWithAnalysisManager(G4VAnalysisManager*);
0072     DamageMap GetDamageMap() { return fDirectDamageMap; }
0073     void ClearDamageMap() { fDirectDamageMap.clear(); }
0074 
0075     void Initialize(G4HCofThisEvent*) override;
0076     void EndOfEvent(G4HCofThisEvent*) override;
0077     void Clear();
0078     void DrawAll() override;
0079     void PrintAll() override;
0080     void AbsorbResultsFromWorkerScorer(G4VPrimitiveScorer*);
0081     void OutputAndClear(G4double, G4double);
0082     void SetNewValue(G4UIcommand*, G4String) override;
0083 
0084     void ASCII(G4double, G4double);
0085 
0086   private:
0087     G4int fnbOfEvents = 0;
0088     G4bool fDNAInserted = false;
0089     G4double fBreakEnergy = 17.5 * eV;
0090     G4double fEnergyDeposit = 0;
0091     G4double* fRadius = nullptr;
0092 
0093     G4String fOutputName = "DirectDamageInfo";
0094     G4String fOutputType = "ascii";
0095     DamageMap fDirectDamageMap;
0096     DamageMap fIndirectDamageMap;
0097     EnergyDepositMap fEnergyDepositMap;
0098 
0099     G4UIcmdWithAString* fpOutputFileUI = nullptr;
0100     G4UIcmdWithAString* fpOutputTypeUI = nullptr;
0101     G4UIcmdWithADoubleAndUnit* fpBreakEnergyUI = nullptr;
0102 
0103     DetectorConstruction* fpDetector = nullptr;
0104     std::map<G4int, G4double> fDoseArray;
0105 
0106     MoleculeInserter* fpGun = nullptr;
0107 
0108   protected:
0109     G4bool ProcessHits(G4Step*, G4TouchableHistory*) override;
0110 };
0111 
0112 //....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
0113 
0114 #endif