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Warning, /geant4/examples/advanced/dna/moleculardna/human_cell_HTB177.mac is written in an unsupported language. File is not indexed.

0001 ### HTB177 cell line - irradiation with He4 ions
0002 
0003 #
0004 # See more details on moleculardna specific UI commands:
0005 # - https://geant4-dna.github.io/molecular-docs/docs/overview/configuration
0006 # - https://geant4-dna.github.io/molecular-docs/docs/overview/macro-anatomy
0007 # - the README file
0008 # - the messenger classes of the moleculardna example
0009 #
0010 
0011 # Physics: choice of thermalization model
0012 /process/dna/e-SolvationSubType Meesungnoen2002
0013 #/process/dna/e-SolvationSubType Ritchie1994
0014 #/process/dna/e-SolvationSubType Terrisol1990
0015 
0016 # Verbosity: settings
0017 /run/verbose 1
0018 /control/verbose 1
0019 
0020 # Chemistry: selection of IRT_syn
0021 /process/chem/TimeStepModel IRT_syn
0022 
0023 # Chemistry: end time of chemistry stage
0024 /scheduler/endTime 5.0 ns
0025 
0026 # Chemistry: set maximum allowed zero time steps
0027 /scheduler/maxNullTimeSteps 10000000
0028 
0029 # Geometry: size of World volume
0030 /world/worldSize 50 um
0031 
0032 # Geometry: shape of the cell
0033 /cell/radiusSize 17 2.5 13 um
0034 
0035 # Geometry: creation
0036 # See https://geant4-dna.github.io/molecular-docs/docs/examples/bacterial-cell
0037 #  - Side length for each placement
0038 /dnageom/placementSize 77 77 77 nm
0039 #  - Scaling of XYZ in fractal definition file
0040 /dnageom/fractalScaling 77 77 77 nm
0041 #  - Path to file that defines placement locations
0042 /dnageom/definitionFile geometries/cube-centred-X-8.txt
0043 #  - Set placement volumes
0044 /dnageom/placementVolume turn geometries/turned_solenoid_770_withHistone.txt
0045 /dnageom/placementVolume turntwist geometries/turned_twisted_solenoid_770_withHistone.txt true
0046 /dnageom/placementVolume straight geometries/straight_solenoid_770_withHistone.txt
0047 
0048 # Geometry: distance from base pairs at which radicals are killed
0049 /dnageom/radicalKillDistance 9 nm
0050 
0051 # Geometry: deposited energy accumulation range limit to start recording SBs from direct effects
0052 /dnageom/interactionDirectRange 2.0 angstrom
0053 
0054 # Damage: model settings
0055 /dnadamage/directDamageLower 5 eV
0056 /dnadamage/directDamageUpper 37.5 eV
0057 
0058 /dnadamage/indirectOHBaseChance 1.0
0059 /dnadamage/indirectOHStrandChance 0.405
0060 /dnadamage/inductionOHChance 0.0
0061 
0062 /dnadamage/indirectHBaseChance 1.0
0063 /dnadamage/indirectHStrandChance 0.0
0064 /dnadamage/inductionHChance 0.0
0065 
0066 /dnadamage/indirectEaqBaseChance 1.0
0067 /dnadamage/indirectEaqStrandChance 0.0
0068 /dnadamage/inductionEaqChance 0.0
0069 
0070 # Analysis: add ellipsoid chromosomal region of interest, with the name "cell"
0071 /chromosome/add cell ellipse 8550 2500 6425 0 0 0 nm 0 0 0
0072 
0073 # Run: initialization
0074 /run/initialize
0075 
0076 # Run: print progress
0077 /run/printProgress 1
0078 
0079 # Source geometry
0080 /gps/pos/type Plane
0081 /gps/pos/shape Circle
0082 /gps/pos/centre 0 3000 0 nm
0083 /gps/pos/rot1 0 0 1
0084 /gps/pos/rot2 1 0 0
0085 /gps/pos/radius 8550 nm
0086 /gps/direction 0 -1 0
0087 
0088 # Source particle
0089 /gps/particle ion
0090 /gps/ion 2 4 2 ### Helium
0091 
0092 # Analysis ROOT output file name, particle energy, beam on
0093 /analysisDNA/fileName HTB5MeV #LET 80.3
0094 /gps/energy 5 MeV
0095 /run/beamOn 150
0096 
0097 /analysisDNA/fileName HTB7p5MeV #65.9
0098 /gps/energy 7.5 MeV
0099 /run/beamOn 180
0100 
0101 /analysisDNA/fileName HTB10MeV #53.3
0102 /gps/energy 10 MeV
0103 /run/beamOn 220
0104 
0105 /analysisDNA/fileName HTB15MeV #39.2
0106 /gps/energy 15 MeV
0107 /run/beamOn 300
0108 
0109 /analysisDNA/fileName HTB20MeV #31.4
0110 /gps/energy 20 MeV
0111 /run/beamOn 390
0112 
0113 /analysisDNA/fileName HTB30MeV #22.8
0114 /gps/energy 30 MeV
0115 /run/beamOn 550
0116 
0117 /analysisDNA/fileName HTB60MeV #13.05
0118 /gps/energy 60 MeV
0119 /run/beamOn 930
0120 
0121 /analysisDNA/fileName HTB261MeV #4
0122 /gps/energy 261 MeV
0123 /run/beamOn 3000